Maceration in Pure Chemistry: Principles, Challenges and Precautions Dr. Navdeep Sharma Institute of Sciences SAGE University, Indore Maceration, a cornerstone in chemical extraction techniques, holds significant value in the field of pure chemistry. This method involves soaking solid materials in a solvent to extract specific compounds, relying on principles like solubility, diffusion and partitioning. Although simple in concept, maceration presents several challenges and requires adherence to strict precautions to ensure the integrity of extracted compounds. In this blog, we explore maceration from the perspective of pure chemistry, discussing its underlying mechanisms, challenges and best practices. Fundamental Chemistry of Maceration Maceration relies on key chemical principles that govern the interaction between the solvent and the solute within a matrix: 1. Solubility and Solvent-Solute Interaction The process begins when the solvent interacts with the solid matri...
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Showing posts from January, 2025
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Maceration: A Traditional yet Timeless Extraction Technique Dr. Navdeep Sharma Institute of Sciences SAGE University, Indore Maceration is one of the oldest and simplest methods of extracting bioactive compounds from plant material. Used widely in herbal medicine, pharmaceuticals and perfumery, maceration involves soaking plant material in a suitable solvent to extract desired compounds. This blog explores the detailed process of maceration, its underlying chemistry and its applications in modern industries. What is Maceration? Maceration is a liquid-solid extraction technique where plant material is immersed in a solvent at ambient or slightly elevated temperatures. Over time, the solvent dissolves the bioactive compounds from the plant matrix, resulting in a solution enriched with these compounds. The process is simple yet effective, making it suitable for small-scale and traditional extraction setups. Key Principles of Maceration Solubility: The success of macer...
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Solvent Extraction of Tulsi: Capturing the Essence of Holy Basil Dr. Navdeep Sharma Institute of Sciences SAGE University, Indore Tulsi (Ocimum sanctum), also known as Holy Basil, is revered in traditional medicine for its extensive therapeutic properties. It is known for its adaptogenic, antimicrobial and anti-inflammatory effects, making it a staple in Ayurveda and modern wellness industries. Solvent extraction is an effective method for isolating Tulsi’s bioactive compounds, including eugenol and ursolic acid, which are widely used in pharmaceuticals, nutraceuticals and cosmetics. This blog explores the step-by-step process of solvent extraction for Tulsi and its versatile applications. Why Tulsi? Tulsi contains a rich spectrum of bioactive compounds that offer numerous health benefits: Eugenol: A phenolic compound with antimicrobial and anti-inflammatory properties. Ursolic Acid: Known for its anti-cancer and anti-inflammatory effects. Flavonoid...